Can tuples with multiple elements be used as keys in a dictionary?

Yes, a tuple with multiple elements can be used as a key in a dictionary if all elements of the tuple are immutable (hashable) data types. Tuples themselves are immutable and hashable if their contents are also hashable.

Example:

my_dict = {('a', 1): 'value1', ('b', 2): 'value2'}
print(my_dict[('a', 1)])  # Outputs 'value1'

If the tuple contains mutable objects, such as lists, then such a tuple cannot be used as a key.