Is it possible to use CSS Grid and Flexbox together?

Yes, CSS Grid and Flexbox can be used together, and it is often even recommended for creating complex and responsive layouts.

• CSS Grid is great for building the overall structure of the page — for example, placing main areas (header, sidebar, content, footer).
• Flexbox is better used for aligning and distributing elements within these areas — for example, for menus, buttons, cards.

Example:

.container {
  display: grid;
  grid-template-columns: 200px 1fr;
  grid-template-rows: 60px 1fr 40px;
  height: 100vh;
}
.sidebar {
  grid-column: 1;
  grid-row: 1 / 4;
  display: flex;
  flex-direction: column;
  justify-content: space-between;
}
.content {
  grid-column: 2;
  grid-row: 2;
  display: flex;
  flex-wrap: wrap;
  gap: 10px;
}

Thus, Grid sets the main grid, and Flexbox manages the layout of elements inside the cells.